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EFFECT OF 10% CARBAMIDE PEROXIDE ON DENTIN

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Abstract

ÃÖ±Ù µé¾î ½É¹ÌÀû ¸ñÀûÀ¸·Î Ä¡¾Æ ¹Ì¹éÁ¦¸¦ ÀÌ¿ëÇÑ Ä¡¾Æ ¹Ì¹é¼úÀÌ ³Î¸® »ç¿ëµÇ°í ÀÖ´Ù. ÇöÀç±îÁö Ä¡¾Æ ¹Ì¹é°èÀÇ Á¤È®ÇÑ ±âÀüÀº ¹àÇôÁ® ÀÖÁö ¾ÊÁö¸¸ ¹Ì¹éÁ¦·ÎºÎ·¯ ¿©·¯ °¡Áö ¹æ¹ýÀ¸·Î ºÐÇØµÈ free radicalÀÇ º¹ÀâÇÑ »êÈ­ÀÛ¿ë¿¡ ÀÇÇÑ °ÍÀ¸·Î, Ä¡¾Æº¯»öÀÇ ¿øÀι°ÁúÀÇ È­ÇÐÀû ±¸Á¶°¡ ¹Ù²î¾îÁüÀ¸·Î½á Èñ°Ô µÇ´Â °ÍÀ¸·Î ÀÌÇØÇÏ°í ÀÖ´Ù. º» ¿¬±¸ÀÇ º¹ÀûÀº Ä¡¾Æ ¹Ì¹éÁ¦¿¡ ÀÇÇÑ »ó¾ÆÁúÀÇ Æ¯¼ºº¯È­¸¦ °üÂûÇÏ°í ¹Ì¹éÁ¦ÀÇ ¾ÈÀü¼ºÀ» Æò°¡ÇÏ°íÀÚ ÇÏ¿´´Ù. À̸¦ À§ÇØ 10% carbamide peroxide¸¦ 1ÀÏ¿¡ 6½Ã°£ 2ÁÖµ¿¾È »ç¶÷ÀÇ ¼Ò±¸Ä¡ ¹ý¶ûÁú¿¡ Àû¿ëÇÑ ÈÄ »ó¾ÆÁú¿¡¼­ ³ªÅ¸³ª´Â Çü»óº¯È­, °æµµº¯È­, Á¶¼ºº¯È­ ¹× ¹«±âÁú ÇÔ·®º¯È­¸¦ ÁÖ»çÀüÀÚÇö¹Ì°æ(SEM), ¹Ì¼¼°æµµ±â, FT-Raman ºÐ±¤±â ±×¸®°í ÀüÀÚŽħ¹Ì¼¼ºÐ¼®±â(EPMA)¸¦ ÀÌ¿ëÇÏ¿© ºÐ¼®ÇÏ°í ´ÙÀ½°ú °°Àº °á°ú¸¦ ¾ò¾ú´Ù.i ¹ý¶ûÁú Ç¥¸é¿¡ µµÆ÷ÇÑ 10% carbamide peroxide°¡ »ó¾ÆÁú·Î ħÅõÇÏ¿© ¹ÌÄ£ ¿µÇâÀº Áõ·ù¼ö¿¡¸¸ ´ã°¡µÐ ½Ã·á¿Í ºñ±³ÇÏ¿´À» ¶§ Çü»óº¯È­ÀÇ Ãø¸é¿¡¼­´Â Â÷À̸¦ ¹ß°ßÇÒ ¼ö ¾ø¾ú´Ù. Peritubutar dentin°ú intertubular dentinÀÇ Ç¥¸é¿¡¼­´Â nanometer range¿¡¼­ ¾Æ¹«·± º¯È­¸¦ ¹ß°ßÇÒ ¼ö ¾ø¾ú´Ù. ¹Ì¹éó¸®ÇÑ Ä¡¾Æ¿Í Áõ·ù¼ö¿¡¸¸ ´ã°¡µÐ Ä¡¾ÆÀÇ »ó¾ÆÁú¿¡¼­ Åë°èÀûÀ¸·Î À¯ÀÇÇÑ °æµµÀÇ Â÷À̸¦ ¹ß°ßÇÒ ¼ö ¾ø¾ú´Ù. FT-RamanºÐ¼®°á°ú »ó¾ÆÁú ±¸¼º¼ººÐ Áß ¾î¶² º¯È­µµ ºÐ±¤ÇÐÀûÀ¸·Î °üÂûµÇÁö ¾Ê¾Ò´Ù. À¯±âÁú¿¡ ÀÇÇÑ peak¿Í ¹«±âÁú¿¡ ÀÇÇÑ peak¸ðµÎ ¹«½ÃÇÒ ¼ö ÀÖÀ» Á¤µµÀÇ Raman intensity º¯È­¸¸ °üÂûµÇ¾ú´Ù. ¹«±âÁú ÇÔ·®º¯È­¸¦ ÃøÁ¤ÇÑ °á°ú ¾Æ¹«·± 󸮵µ ÇÏÁö ¾ÊÀº Ä¡¾ÆÀÇ »ó¾ÆÁú, Áõ·ù¼ö¿¡¸¸ ´ã°¡µÐ Ä¡¾ÆÀÇ »ó¾ÆÁú ±×¸®°í ¹Ì¹éÈÄ Áõ·ù¼ö¿¡ ´ã°¡µÐ Ä¡¾ÆÀÇ »ó¾ÆÁú¿¡¼­ ¹«±âÁú ÃÑ·®ÀÌ °¢°¢ 98.73¡¾ 1.89, 98.56¡¾2.11, 97.47¡¾2.51·Î ³ªÅ¸³µ´Ù. ÀÌµé °ªÀº Åë°èÇÐÀûÀ¸·Î À¯ÀÇÇÑÂ÷À̸¦º¸ÀÌÁö ¾Ê¾Ò´Ù.
ÀÌ»óÀÇ °á°úµé·Î º¼ ¶§ 10% carbamide peroxide¹Ì¹éÀÌ »ó¾ÆÁú¿¡ ¹ÌÄ¡´Â ¿µÇâÀº ±ØÈ÷ ¹Ì¾àÇÏ´Ù°í ÆÇ´ÜµÇ¾î »ó¾ÆÁú¿¡´Â ¾ÈÀüÇÑ °ÍÀ¸·Î »ý°¢µÈ´Ù.
The teeth bleaching with bleaching agent is widely used at recent times. Until yet the exact mechanism of the bleaching agent isa t known but it is thought that is by the complex reduction-oxidation reaction of the decomposed free radical from bleaching agent through various ways. In other words, it is supposed that the teeth are whitened by agent¢¥ s changing chemical structures of stain-causing materials. The purpose of this study is to ex-am the change of the dentinal character by bleaching agent and to evaluate the safety of this agent. For this study, after applying 10% carbamide peroxide to enamel of human premolar for 6 hours a day for 2 weeks we examined changes of surface morphology, microhardness, composition and contents of minirals in human dentin using SEM, microhardness tester, FT-Raman spectrometer and EPMA and got following results.
There was no significant difference in surface morphologic change when we examined the effect of 10% carbamide peroxide which penetrated into dentin after applied on enamel surface comparing with result from specimen in distilled water. No change was shown on the surface of peritubular and intertubular dentin within the nanometeric range. The microhardness between bleached teeth and teeth stored in distilled water showed no statistically significant difference. FT Raman spectra of dentin exhibited no change of the component in human dentin. Only the least change in peaks of organic and inorganic materials were detected in Raman intencity. The total content of mineral elements in dentin with no treatment. stored only in distilled water and stored in distilled water after bleaching were 98.73¡¾1.89, 98.56¡¾2.11 and 97.47¡¾2.51 respectively. Also they showed no statistically significant difference.
From above results, the effect of 10% carbamide peroxide bleaching on structure of dentin is very low and the results may confirm the safety of this bleaching agent.

Å°¿öµå

Ä¡¾Æ ¹Ì¹é;10% carbamide peroxide;»ó¾ÆÁú;FT-Raman ºÐ±¤±â;¹Ì¼¼°æµµ;Bleaching;Dentin;FT-Raman spectrometer;Microhardness

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